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The Drug-Induced Respiratory Disease Website

Corresponds to circulating autoantibodies (ANA, anti-dsDNA, multispecific ANCA). Titers can be very high and/or multispecific and tend to diminish in a few weeks or months upon drug discontinuance. Autoimmunity can be asymptomatic or is with various clinical presentations including pulmonary vascultis or hemorrhage (PMID 20015613). See also under patterns IIIa, IIIb, IIId, Vd, VId, and  Xb, d, h, j, m, s, x, y, ac, ah, am, ao, aw, ax, ay

Publications

Mili? R, Plavec G, Tufegdzi? I, Tomi? I, Sarac S, Loncarevi? O

Nitrofurantoin-induced immune-mediated lung and liver disease.

Vojnosanitetski pregled 2012 Jun;69;536-40 — 2012 Jun — 536-40

Mendez JL, Nadrous HF, Hartman TE, Ryu JH

Chronic nitrofurantoin-induced lung disease.

Mayo Clinic proceedings 2005 Oct;80;1298-302 — 2005 Oct — 1298-302