The Drug-Induced Respiratory Disease Website
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.a Autoimmunity - An autoimmune condition (+ANA, +anti-ds-DNA, +ANCAs, other auto-Abs)
XII. Pericardial involvement
XII.c Hemopericardium - Bloody pericardial effusion
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
III. Myocardial ischemia - Coronary artery disease
III.a Coronary artery disease (acute) - Myocardial ischemia/infarction
VI. Cardiomyopathy
VI.b Hypertrophic cardiomyopathy
IX. Endocardial involvement
IX.a Endocarditis (infective)
X. Pulmonary edema
X.b Pulmonary edema, noncardiogenic (NCPE)
XI. Pulmonary vasculopathies
XI.a Pulmonary arterial hypertension
XI. Pulmonary vasculopathies
XI.b Acute pulmonary hypertension
XI. Pulmonary vasculopathies
XI.e Pulmonary artery aneurysm(s)
XI. Pulmonary vasculopathies
XI.i Pulmonary veno-occlusive disease
XIII. Thrombosis - Embolism
XIII.h Mercury pulmonary embolism
XIII. Thrombosis - Embolism
XIII.k Foreign body pulmonary vasculopathy (Excipient lung disease)
XV. Chest pain
XV.a Chest pain (acute or subacute), lone or prominent
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XXI. Mediastinal involvement/injury
XXI.c Pneumomediastinum
XXI. Mediastinal involvement/injury
XXI.d Mediastinitis
XXVI. Neuromuscular dysfunction
XXVI.c Acute myelopathy (can cause ARF)
XXX. Imaging features
XXX.f Imaging: Alveolar opacities or haze with a batwing or butterfly distribution
XXXI. Eye catchers
XXXI.e Eye catcher: A batwing or butterfly pattern on chest imaging
XXXIII. Histopathology (for pulmonary pathology see in ‘Pneumotox’ (a free companion App)
XXXIII.l Path: Pulmonary hypertension incl. angiomatoid vasculopathy
XXXIII. Histopathology (for pulmonary pathology see in ‘Pneumotox’ (a free companion App)
XXXIII.n Path: Foreign body embolism, microangiopathy, vasculopathy
XXXIV. Infections
XXXIV.a Septic pulmonary embolism
XXXVIII. Miscellaneous - Varia
XXXVIII.w Foreign body (talc, constarch) retinopathy
XII. Pericardial involvement
XII.g Pleural/pericardial effusion, ANA positive (DI lupus)
XIV. Pleural involvement
XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XIV. Pleural involvement
XIV.h Pleural thickening - Fibrothorax
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.j Organizing pneumonia (OP/BOOP) pattern (an area or areas of consolidation on imaging)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.d Subclinical ANA positivity
II. Myocardial dysfunction - Heart failure
II.d Cardiovascular collapse - Cardiogenic shock - Hypotension
X. Pulmonary edema
X.b Pulmonary edema, noncardiogenic (NCPE)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)
XXXVIII. Miscellaneous - Varia
XXXVIII.m Metabolic acidosis (incl. lactic acidosis/-gap). May cause hyperpnea/dyspnea
XXXIX. Rechallenge
XXXIX.a Rechallenge can lead to near-fatal or fatal relapse of AE/ILD
XXXIX. Rechallenge
XXXIX.b Rechallenge can lead to relapse of AE/ILD
XV. Chest pain
XV.a Chest pain (acute or subacute), lone or prominent
XXVIII. Large airway involvement
XXVIII.a Angioedema (may cause UAO, asphyxia and death)
XXXII. Esophageal pathology
XXXII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula, Boerhaave’s syndrome)
XXXII. Esophageal pathology
XXXII.e Esophageal toxicity