Philippe Camus, M.D.

Dijon, France

Back to drug

The Drug-Induced Respiratory Disease Website

XXXVIII.m

Metabolic acidosis (incl. lactic acidosis/-gap). May cause hyperpnea/dyspnea

See also under IXg and h. Salbutamol/albuterol and methanol are notable for inducing lactic acidosis and anion gap. Reactional dyspnea and/or hyperpnea can be present. To quote Klig et al. (2014) (PMID 25140963) 'The differential diagnosis of an elevated anion-gap metabolic acidosis is detailed by the acronym 'CAT MUDPILES''. Review of drug-induced AB disorders at PMID 25370778

Publications

Cole JL

Acetazolamide Causes Worsening Acidosis in Uncompensated COPD Exacerbations: Increased Awareness Needed for Patient Safety.

The Journal of emergency medicine 2020 Mar 30;; — 2020 Mar 30

Adamson R, Swenson ER

Acetazolamide Use in Severe Chronic Obstructive Pulmonary Disease. Pros and Cons.

Annals of the American Thoracic Society 2017 Jul;14;1086-1093 — 2017 Jul — 1086-1093

Prieto de Paula JM, Franco Hidalgo S, Borge Gallardo L, Mayor Toranzo E

The importance of identifying the association between metabolic alkalosis and respiratory acidosis.

Archivos de bronconeumologia 2012 Feb;48;65-6 — 2012 Feb — 65-6

Heller I, Halevy J, Cohen S, Theodor E

Significant metabolic acidosis induced by acetazolamide. Not a rare complication.

Archives of internal medicine 1985 Oct;145;1815-7 — 1985 Oct — 1815-7

Sporn A, Scothorn DM, Terry JE

Metabolic acidosis induced by acetazolamide.

Journal of the American Optometric Association 1991 Dec;62;934-7 — 1991 Dec — 934-7