The Drug-Induced Respiratory Disease Website

Acetazolamide

Cardiovascular collapse - Cardiogenic shock - Hypotension

See also under Xf and XIIe, , f, g, k, l, o, s, t, ad, ag

Zimmermann S, Achenbach S, Wolf M, Janka R, Marwan M, Mahler V

Recurrent shock and pulmonary edema due to acetazolamide medication after cataract surgery.

Heart & lung : the journal of critical care 2014 Mar-Apr;43;124-6 — 2014 Mar-Apr — 124-6

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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