The Drug-Induced Respiratory Disease Website
Corresponds to circulating autoantibodies (ANA, anti-dsDNA, multispecific ANCA). Titers can be very high and/or multispecific and tend to diminish in a few weeks or months upon drug discontinuance. Autoimmunity can be asymptomatic or is with various clinical presentations including pulmonary vascultis or hemorrhage (PMID 20015613). See also under patterns IIIa, IIIb, IIId, Vd, VId, and Xb, d, h, j, m, s, x, y, ac, ah, am, ao, aw, ax, ay
Publications
What is the utility of routine ANA testing in predicting development of biological DMARD-induced lupus and vasculitis in patients with rheumatoid arthritis? Data from a single-centre cohort.
Annals of the rheumatic diseases 2014 Sep;73;1695-9 — 2014 Sep — 1695-9