The Drug-Induced Respiratory Disease Website
(Fr: SDRA sur critères gazométriques PaO2/FIO2). May overlap with Ia. Mechanical ventilation commonly needed. ECMO required in some instances (PMID 29967877). ARDS definition and grading at PMID 22797452. ARDS (and formerly ALI) are defined on the basis of gas exchange abnormalities. Thus, ARDS is not a well-characterized disease entity and may arise in widely disparate clinical scenarios. Pathologically, ARDS may correspond to DAD, pulmonary edema, acute NSIP-like ILD w/wo granulomas, -eosinophilic pneumonia (AEP), AFOP, amiodarone pulmonary toxicity, DAH, fat or silicone embolism, AIP, radiation injury, pulmonary fibrosis exacerbated by drugs or surgery (see under specific patterns) and drug- or alcohol-induced aspiration pneumonitis (see under XIg). Appropriate tests and BAL help exclude an infection and separate these entities. Some patients respond to intravenous corticosteroid therapy. Review at PMID 1939859. See also under IL 'Diffuse Alveolar Damage', XIg, XVf and under 'Postoperative ARDS'
Publications
Acute respiratory distress syndrome caused by salicylate intoxication.
Clinical case reports 2018 Sep;6;1905-1906 — 2018 Sep — 1905-1906
Salicylate-induced pulmonary edema--a near-miss diagnosis.
The American journal of emergency medicine 2014 May;32;490.e5-6 — 2014 May — 490.e5-6
Current management of salicylate-induced pulmonary edema.
Southern medical journal 2011 Mar;104;225-32 — 2011 Mar — 225-32
Recurrent ARDS in a 39-year-old woman with migraine headaches.
Chest 1998 Sep;114;919-22 — 1998 Sep — 919-22
Late diagnosis of chronic salicylate intoxication.
Lancet (London, England) 1993 Sep 11;342;687 — 1993 Sep 11 — 687
Salicylate-induced pulmonary edema. Clinical features and prognosis.
Annals of internal medicine 1981 Oct;95;405-9 — 1981 Oct — 405-9
Acute respiratory failure during therapy for salicylate intoxication.
Annals of emergency medicine 1981 Feb;10;104-6 — 1981 Feb — 104-6
Adult respiratory distress syndrome induced by salicylate toxicity.
Postgraduate medicine 1985 Jul;78;117-9, 123 — 1985 Jul — 117-9, 123
Bronchoalveolar lavage in recurrent aspirin-induced adult respiratory distress syndrome.
Chest 1986 Sep;90;452-3 — 1986 Sep — 452-3
Acute salicylate self-poisoning in 177 consecutive patients treated in ICU.
Acta anaesthesiologica Scandinavica 1987 May;31;312-6 — 1987 May — 312-6
Fatal respiratory-distress syndrome and salicylate intoxication in a two-year-old.
Lancet (London, England) 1979 Nov 24;2;1131-2 — 1979 Nov 24 — 1131-2