The Drug-Induced Respiratory Disease Website
Acute/chronic. Due to the high background incidence rate of naturally-occurring VTE, a cause-and-effect relationship with drugs or procedures may be difficult to establish firmly. Epidemiologic studies can be supportive (PMID 25924683). A search for antiphospholipid antibodies is indicated. Chronic iatrogenic thromboembolism, for instance in patients with cardiac wires and leads may cause thromboembolic pulmonary hypertension (PMID 24881082)
Publications
Diaz-Padilla I, Siu LL, San Pedro-Salcedo M, Razak AR, Colevas AD, Shepherd FA, Leighl NB, Neal JW, Thibault A, Liu L, Lisano J, Gao B, Lawson EB, Wakelee HA
A phase I dose-escalation study of aflibercept administered in combination with pemetrexed and cisplatin in patients with advanced solid tumours.
British journal of cancer 2012 Aug 07;107;604-11 — 2012 Aug 07 — 604-11