The Drug-Induced Respiratory Disease Website
DRESS stands for 'Drug Rash, Eosinophilia, Systemic Symptoms or Syndrome'. Includes internal organ involvement (liver, bone marrow, kindney, lung, heart in the form of myocarditis (PMID 21658796)) and occasionally MOF/MODS. Respiratory involvement (in about 15% of the patients), is in the form of cough, dyspnea, wheezing, pleural effusion, pulmonary infiltrates or PIE. See also under eosinophilic pneumonia. A precise definition of the syndrome has been available since 1996 (Bocquet et al.). Earlier cases of 'Drug Hypersensitivity' in the literature likely represent authentic DRESS cases. Review and lists of causal drugs at PMID 21592453, 26354734. Reviews at PMID 23602182, 23602183, 25592341, 30140942. Pulmonary manifestations at PMID 31662996. Causal drugs at PMID 32247873 and 35160164.
the heart in DRESS @ PMID 35160164.
Publications
[Rash, fever, eosinophilia and elevated liver enzymes. DRESS syndrome (drug reaction or rash with eosinophilia and systemic symptoms)].
Praxis 2010 Jun 23;99;767-77; quiz 776 — 2010 Jun 23 — 767-77; quiz 776
Multiple system reaction to trimethoprim-sulfamethoxazole.
Southern medical journal 1987 Feb;80;275-6 — 1987 Feb — 275-6
Fatal multisystem toxicity after co-trimoxazole.
Lancet (London, England) 1978 Apr 15;1;831 — 1978 Apr 15 — 831
Multisystem toxicity after co-trimoxazole.
Lancet (London, England) 1978 Sep 23;2;682-3 — 1978 Sep 23 — 682-3