The Drug-Induced Respiratory Disease Website
Pericarditis (i.e. pericardial inflammation) is usually heralded by acute mediothoracic chest pain (PMID 10878205). Large effusions can be ANA positive and cause pericardial tamponade. When present as a longterm sequela, pericardial thickening may cause restriction and constriction. See also under Vc, d, g, m and XIIk (PMID 20511488, 23376916)
Publications
ANA-Negative Hydralazine-Induced Pericardial Effusion.
Case reports in medicine 2017;2017;3521541 — 2017 — 3521541
Rheumatic and febrile syndrome during prolonged hydralazine treatment.
Journal of the American Medical Association 1954 Jan 02;154;23-9 — 1954 Jan 02 — 23-9
Isoniazid-induced lupus erythematosus presenting with cardiac tamponade.
American journal of therapeutics 2002 Mar-Apr;9;163-5 — 2002 Mar-Apr — 163-5
Pericardial tamponade: a major presenting manifestation of hydralazine-induced lupus syndrome.
The American journal of medicine 1973 Jan;54;84-7 — 1973 Jan — 84-7