The Drug-Induced Respiratory Disease Website
Acute/chronic. Due to the high background incidence rate of naturally-occurring VTE, a cause-and-effect relationship with drugs or procedures may be difficult to establish firmly. Epidemiologic studies can be supportive (PMID 25924683). A search for antiphospholipid antibodies is indicated. Chronic iatrogenic thromboembolism, for instance in patients with cardiac wires and leads may cause thromboembolic pulmonary hypertension (PMID 24881082)
Publications
Clozapine-Associated Pulmonary Embolism: A High-Mortality, Dose-Independent and Early-Onset Adverse Effect.
American journal of therapeutics 2018 Jul/Aug;25;e434-e438 — 2018 Jul/Aug — e434-e438
Clozapine-induced recurrent pulmonary thromboembolism.
The Journal of neuropsychiatry and clinical neurosciences 2013;25;E50-1 — 2013 — E50-1
A case of cardiac arrest and pulmonary embolism after clozapine titration.
The primary care companion for CNS disorders 2011;13; — 2011
Nonfatal pulmonary embolus associated with clozapine treatment: a case series.
General hospital psychiatry 2011 Jan-Feb;33;85.e5-6 — 2011 Jan-Feb — 85.e5-6
Pulmonary embolism in a patient taking clozapine.
BMJ (Clinical research ed.) 2008 Jun 28;336;1499-501 — 2008 Jun 28 — 1499-501
Massive pulmonary embolism in a young patient on clozapine therapy.
The Journal of emergency medicine 2004 Jul;27;27-9 — 2004 Jul — 27-9
Clozapine and pulmonary embolism.
Acta psychiatrica Scandinavica 2003 Jul;108;76-7; discussion 77 — 2003 Jul — 76-7; discussion 77
Clozapine therapy and pulmonary embolism.
Canadian journal of psychiatry. Revue canadienne de psychiatrie 2000 May;45;395 — 2000 May — 395
Association of venous thromboembolism and clozapine.
Lancet (London, England) 2000 Apr 01;355;1155-6 — 2000 Apr 01 — 1155-6
[Clozapine and myocarditis].
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 1995 Oct 10;115;3026-7 — 1995 Oct 10 — 3026-7