The Drug-Induced Respiratory Disease Website
DRESS stands for 'Drug Rash, Eosinophilia, Systemic Symptoms or Syndrome'. Includes internal organ involvement (liver, bone marrow, kindney, lung, heart in the form of myocarditis (PMID 21658796)) and occasionally MOF/MODS. Respiratory involvement (in about 15% of the patients), is in the form of cough, dyspnea, wheezing, pleural effusion, pulmonary infiltrates or PIE. See also under eosinophilic pneumonia. A precise definition of the syndrome has been available since 1996 (Bocquet et al.). Earlier cases of 'Drug Hypersensitivity' in the literature likely represent authentic DRESS cases. Review and lists of causal drugs at PMID 21592453, 26354734. Reviews at PMID 23602182, 23602183, 25592341, 30140942. Pulmonary manifestations at PMID 31662996. Causal drugs at PMID 32247873 and 35160164.
the heart in DRESS @ PMID 35160164.
Publications
Drug reaction with eosinophilia and systemic symptoms (DRESS) with severe and atypical lung involvement.
Radiology case reports 2020 Nov;15;2178-2182 — 2020 Nov — 2178-2182
Piñana E, Lei SH, Merino R, Melgosa M, De La Vega R, Gonzales-Obeso E, Ramírez E, Borobia A, Carcas A
DRESS-syndrome on sulfasalazine and naproxen treatment for juvenile idiopathic arthritis and reactivation of human herpevirus 6 in an 11-year-old Caucasian boy.
Journal of clinical pharmacy and therapeutics 2010 Jun;35;365-70 — 2010 Jun — 365-70
Hypersensitivity reactions to non-steroidal anti-inflammatory drugs.
Current drug metabolism 2009 Nov;10;971-80 — 2009 Nov — 971-80
De Weck AL, Sanz ML, Gamboa PM, Aberer W, Blanca M, Correia S, Erdman S, Jermann JM, Kanny G, Kowalski M, Mayorga L, Medrala W, Merk A, Sturm GJ, Sainte-Laudy J, Schneider MS, Sczczeklik A, Weber JM, Wedi A
Nonsteroidal anti-inflammatory drug hypersensitivity syndrome. A multicenter study. I. Clinical findings and in vitro diagnosis.
Journal of investigational allergology & clinical immunology 2009;19;355-69 — 2009 — 355-69