The Drug-Induced Respiratory Disease Website
Typically noncardiac. Includies chest tightness. See also under pill-induced esophageal pathologies under XIh, XIi, XIk and XIax that may cause substernal pain. Dedicated review at PMID 9403280. See also under Vi. Can be substernal, or in other areas of the chest. Can be acute, transfixiating and worrisome. Sometimes called 'acute chest syndrome'. Lung findings on imaging can be minimal. Depending on drug and patient, this may correspond to acute pleuritis or pleuro-pneumonitis, subpleural consolidation, GERD, pulmonary vasospasm, tracheal irritation, acute coronary syndrome or remain unexplained (PMID 30697107). See also under pleuritic chest pain (XIc), drug-induced lupus, pleuro-pulmonary lupus and acute coronary syndrome. Differential diagnosis on imaging at PMID 26373647
Publications
Predictors and Diagnostic Significance of the Adenosine Related Side Effects on Myocardial Perfusion SPECT/CT Imaging.
Molecular imaging and radionuclide therapy 2014 Oct 05;23;89-95 — 2014 Oct 05 — 89-95
Intraoperative bronchospasm after intravenous adenosine during general anesthesia.
Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists 2004 Dec;42;237-40 — 2004 Dec — 237-40