The Drug-Induced Respiratory Disease Website
See PMID 29369189. (Fr: PnP a eosinophiles). See also under Ie (Acute eosinophilic pneumonia), Xa (DRESS), XVb and XIXc. DI PIE may manifest with fever, dyspnea and wheezes. Eosinophilia can be present in blood, BAL and/or tissue (XVb). Blood and BAL eosinophilia (XIXc) may suffice to secure the diagnosis without recourse to the lung biopsy. Imaging is similar to PIE of other causes. PIE can be part of the DRESS syndrome (Xa), a systemic illness with a cutaneous rash, hematologic abnormalities and deep-seated organ involvement. A few drugs may cause PIE and eosinophilic granulomatosis and polyangiitis (EGPA) formerly known as the Churg-Strauss syndrome) (Xh). Drugs causing eosinophilia at PMID 15062599, 30256812
Publications
Eosinophilic pneumonia induced by non-steroidal anti-inflammatory drugs: An underestimated risk.
Therapie 2018 Dec;73;473-482 — 2018 Dec — 473-482
[Pulmonary infiltrates with blood eosinophilia in a 62-year-old patient].
Der Internist 2003 Aug;44;1037-41 — 2003 Aug — 1037-41
Diclofenac (Voltaren)-induced eosinophilic pneumonitis. Case report and review of the literature.
Archives of internal medicine 1993 Jul 26;153;1649-52 — 1993 Jul 26 — 1649-52