The Drug-Induced Respiratory Disease Website
(Fr: PnP éosinophilique aiguë). See also under Ic: 'Eosinophilic pneumonia'. May cause ARF and ARDS. MV and/or ECMO may be needed. AEP is with diffuse pulmonary opacities, blood/BAL eosinophilia, pleural effusion and rapidly-progressive respiratory failure in the absence of a cause other than a drug or abused substance (e.g. parasitic infection). See also under IIb and XVb. Separating drug-induced vs. idiopathic AEP can be problematic (PMID 2761601)
Publications
Seventeen Cases of Daptomycin-Induced Eosinophilic Pneumonia in a Cohort of Patients Treated for Bone and Joint Infections: Proposal for a New Algorithm.
Open forum infectious diseases 2022 Nov;9;ofac577 — 2022 Nov — ofac577
Eosinophilic pneumonia: a case of daptomycin induced lung injury.
Journal of community hospital internal medicine perspectives 2021 Mar 23;11;280-285 — 2021 Mar 23 — 280-285
Acute Eosinophilic Pneumonia: A Rare Complication of Daptomycin Therapy.
Cureus 2020 Jan 28;12;e6803 — 2020 Jan 28 — e6803
Drug-induced eosinophilic pneumonia: A review of 196 case reports.
Medicine 2018 Jan;97;e9688 — 2018 Jan — e9688
Acute Eosinophilic Pneumonia: Correlation of Clinical Characteristics With Underlying Cause.
Chest 2017 08;152;379-385 — 2017 08 — 379-385
[Acute eosinophilic pneumonia secondary to daptomycin].
Enfermedades infecciosas y microbiologia clinica 2016 Jun-Jul;34;390-1 — 2016 Jun-Jul — 390-1
Daptomycin-induced acute eosinophilic pneumonia.
WMJ : official publication of the State Medical Society of Wisconsin 2014 Oct;113;199-201 — 2014 Oct — 199-201
Daptomycin-induced eosinophilic pneumonia treated with intravenous corticosteroids.
Journal of pharmacy practice 2015 Jun;28;275-9 — 2015 Jun — 275-9
Daptomycin-associated eosinophilic pneumonia in two patients with prosthetic joint infection.
Surgical infections 2014 Dec;15;834-7 — 2014 Dec — 834-7
Daptomycin-induced acute eosinophilic pneumonia: analysis of the current data and illustrative case reports.
Scandinavian journal of infectious diseases 2013 Oct;45;804-8 — 2013 Oct — 804-8
Eosinophilic pneumonia in patients treated with daptomycin: review of the literature and US FDA adverse event reporting system reports.
Drug safety 2012 Jun 01;35;447-57 — 2012 Jun 01 — 447-57
A rare cause of pulmonary infiltrates one should be aware of: a case of daptomycin-induced acute eosinophilic pneumonia.
Infection 2011 Dec;39;583-5 — 2011 Dec — 583-5
Acute eosinophilic pneumonia secondary to daptomycin: a report of three cases.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2010 Jun 01;50;e63-8 — 2010 Jun 01 — e63-8