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(Fr: PnP éosinophilique aiguë). See also under Ic: 'Eosinophilic pneumonia'. May cause ARF and ARDS. MV and/or ECMO may be needed. AEP is with diffuse pulmonary opacities, blood/BAL eosinophilia, pleural effusion and rapidly-progressive respiratory failure in the absence of a cause other than a drug or abused substance (e.g. parasitic infection). See also under IIb and XVb. Separating drug-induced vs. idiopathic AEP can be problematic (PMID 2761601)

Publications

Pham TT, Garreau R, Craighero F, Cottin V, Said BB, Goutelle S, Ferry T

Seventeen Cases of Daptomycin-Induced Eosinophilic Pneumonia in a Cohort of Patients Treated for Bone and Joint Infections: Proposal for a New Algorithm.

Open forum infectious diseases 2022 Nov;9;ofac577 — 2022 Nov — ofac577

Raman V, Chaudhary I, Shieh S

Eosinophilic pneumonia: a case of daptomycin induced lung injury.

Journal of community hospital internal medicine perspectives 2021 Mar 23;11;280-285 — 2021 Mar 23 — 280-285

Storandt MH, Matta A

Acute Eosinophilic Pneumonia: A Rare Complication of Daptomycin Therapy.

Cureus 2020 Jan 28;12;e6803 — 2020 Jan 28 — e6803

Bartal C, Sagy I, Barski L

Drug-induced eosinophilic pneumonia: A review of 196 case reports.

Medicine 2018 Jan;97;e9688 — 2018 Jan — e9688

De Giacomi F, Decker PA, Vassallo R, Ryu JH

Acute Eosinophilic Pneumonia: Correlation of Clinical Characteristics With Underlying Cause.

Chest 2017 08;152;379-385 — 2017 08 — 379-385

Montenegro O, Del Campo R, Del Rio JJ, Ambrós Checa A

[Acute eosinophilic pneumonia secondary to daptomycin].

Enfermedades infecciosas y microbiologia clinica 2016 Jun-Jul;34;390-1 — 2016 Jun-Jul — 390-1

Patel JJ, Antony A, Herrera M, Lipchik RJ

Daptomycin-induced acute eosinophilic pneumonia.

WMJ : official publication of the State Medical Society of Wisconsin 2014 Oct;113;199-201 — 2014 Oct — 199-201

Chiu SY, Faust AC, Dand HM

Daptomycin-induced eosinophilic pneumonia treated with intravenous corticosteroids.

Journal of pharmacy practice 2015 Jun;28;275-9 — 2015 Jun — 275-9

Yusuf E, Perrottet N, Orasch C, Borens O, Trampuz A

Daptomycin-associated eosinophilic pneumonia in two patients with prosthetic joint infection.

Surgical infections 2014 Dec;15;834-7 — 2014 Dec — 834-7

Phillips J, Cardile AP, Patterson TF, Lewis JS

Daptomycin-induced acute eosinophilic pneumonia: analysis of the current data and illustrative case reports.

Scandinavian journal of infectious diseases 2013 Oct;45;804-8 — 2013 Oct — 804-8

Kim PW, Sorbello AF, Wassel RT, Pham TM, Tonning JM, Nambiar S

Eosinophilic pneumonia in patients treated with daptomycin: review of the literature and US FDA adverse event reporting system reports.

Drug safety 2012 Jun 01;35;447-57 — 2012 Jun 01 — 447-57

Rether C, Conen A, Grossenbacher M, Albrich WC

A rare cause of pulmonary infiltrates one should be aware of: a case of daptomycin-induced acute eosinophilic pneumonia.

Infection 2011 Dec;39;583-5 — 2011 Dec — 583-5

Miller BA, Gray A, Leblanc TW, Sexton DJ, Martin AR, Slama TG

Acute eosinophilic pneumonia secondary to daptomycin: a report of three cases.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2010 Jun 01;50;e63-8 — 2010 Jun 01 — e63-8