The Drug-Induced Respiratory Disease Website

Amiodarone

A mass or masses

(Fr: une ou plusieurs masses). Can be tracer-avid on PET scan and be mistaken for lung cancer.

Carvalho JG, Fernandes C, França M

Organizing pneumonia secondary to amiodarone treatment.

Heliyon 2022 Sep;8;e10630 — 2022 Sep — e10630

Ruangchira-Urai R, Colby TV, Klein J, Nielsen GP, Kradin RL, Mark EJ

Nodular amiodarone lung disease.

The American journal of surgical pathology 2008 Nov;32;1654-60 — 2008 Nov — 1654-60

Jarand J, Lee A, Leigh R

Amiodaronoma: an unusual form of amiodarone-induced pulmonary toxicity.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2007 May 08;176;1411-3 — 2007 May 08 — 1411-3

Arnon R, Raz I, Chajek-Shaul T, Berkman N, Fields S, Bar-On H

Amiodarone pulmonary toxicity presenting as a solitary lung mass.

Chest 1988 Feb;93;425-7 — 1988 Feb — 425-7

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

No activity has been recorded yet.