The Drug-Induced Respiratory Disease Website

Cardiomyopathy (acute, subacute, chronic)

Rare catecholamine-producing adrenal tumors may cause hypertrophic cardiomyopathy (PMID 30557989)

Kim CJ, Kim JM, Jang YH, Shin YS

Cardiomyopathy after local infiltration or application of epinephrine for plastic surgery under general anesthesia : Two cases report.

Korean journal of anesthesiology 2009 Jun;56;725-728 — 2009 Jun — 725-728

Sato Y, Tanaka M, Nishikawa T

Reversible catecholamine-induced cardiomyopathy by subcutaneous injections of epinephrine solution in an anesthetized patient.

Anesthesiology 2000 Feb;92;615-9 — 2000 Feb — 615-9

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

No activity has been recorded yet.