Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website

XI.a

Pulmonary arterial hypertension

May reverse with drug discontinuation. Generally similar to primary PHTn clinically, hemodynamically and on pathology. PMID 23997051. A few cases are thromboembolic in nature (PMID 24881082). Reviews at PMID 29508628, 30545968

Publications

Karch SB, Defraia B, Messerini L, Mari F, Vaiano F, Bertol E

Aminorex associated with possible idiopathic pulmonary hypertension in a cocaine user.

Forensic science international 2014 Jul;240;e7-10 — 2014 Jul — e7-10

Karch SB, Mari F, Bartolini V, Bertol E

Aminorex poisoning in cocaine abusers.

International journal of cardiology 2012 Jul 26;158;344-6 — 2012 Jul 26 — 344-6

Gaine SP, Rubin LJ, Kmetzo JJ, Palevsky HI, Traill TA

Recreational use of aminorex and pulmonary hypertension.

Chest 2000 Nov;118;1496-7 — 2000 Nov — 1496-7

Kramer MS, Lane DA

Aminorex, dexfenfluramine, and primary pulmonary hypertension.

Journal of clinical epidemiology 1998 Apr;51;361-4 — 1998 Apr — 361-4

Brenot F, Herve P, Petitpretz P, Parent F, Duroux P, Simonneau G

Primary pulmonary hypertension and fenfluramine use.

British heart journal 1993 Dec;70;537-41 — 1993 Dec — 537-41

Follath F, Burkart F, Schweizer W

Drug-induced pulmonary hypertension?

British medical journal 1971 Jan 30;1;265-6 — 1971 Jan 30 — 265-6

Kay JM, Smith P, Heath D

Aminorex and the pulmonary circulation.

Thorax 1971 May;26;262-70 — 1971 May — 262-70

Berthou JD, Delahaye JP, Brune J, Dorsit G, Delaye J, Roques JC, Gonin A

[Apparently primary pulmonary arterial hypertension in a woman who had taken appetite depressants (Aminorex)].

Revue de tuberculose et de pneumologie 1972 Sep-Oct;36;944-51 — 1972 Sep-Oct — 944-51

Loogen F, Worth H, Schwan G, Goeckenjan G, Lösse B, Horstkotte D

Long-term follow-up of pulmonary hypertension in patients with and without anorectic drug intake.

Cor et vasa 1985;27;111-24 — 1985 — 111-24

Gurtner HP

[Chronic pulmonary hypertension of vascular etiology, plexogenic pulmonary arteriopathy and the appetite depressant Aminorex: lessons from an epidemic].

Schweizerische medizinische Wochenschrift 1985 Jun 15;115;818-27 — 1985 Jun 15 — 818-27

Gurtner HP

Aminorex and pulmonary hypertension. A review.

Cor et vasa 1985;27;160-71 — 1985 — 160-71

Widgren S

Pulmonary hypertension related to aminorex intake. Histologic, ultrastructural, and morphometric studies of 37 cases in Switzerland.

Current topics in pathology. Ergebnisse der Pathologie 1977;64;1-64 — 1977 — 1-64

Simon H, Felix R

[Reversible pulmonary arterial hypertension after medication of aminorexfumarate (author's transl)].

Medizinische Klinik 1977 Oct 14;72;1685-8 — 1977 Oct 14 — 1685-8

Gurtner HP

Pulmonary hypertension, "plexogenic pulmonary arteriopathy" and the appetite depressant drug aminorex: post or propter?

Bulletin europeen de physiopathologie respiratoire 1979 Sep-Oct;15;897-923 — 1979 Sep-Oct — 897-923