The Drug-Induced Respiratory Disease Website
(Fr: hypoxémie/désaturation isolée). Hypoxemia may reflect 1) Deteriorated VA/Q indicating early lung injury, cell sequestration in the distal pulmonary circulation 2) Ventilatory depression (see under IX a, c, d, e), in this case typically associated with a raise in arterial PCO2. See also under methemoglobinemia, a condition that commonly alters SpO2 readings. Rare instances of spurious hypoxemia from oxygen steal or larceny were described in high-WBC-acute leukemia patients receiving ATRA. Postoperative reopening of the foramen ovale may cause severe hypoxemia, sometimes positional (PMID 30619614)
Publications
Medical outcomes associated with nonmedical use of methadone and buprenorphine.
The Journal of emergency medicine 2013 Aug;45;199-205 — 2013 Aug — 199-205
Improvement in hepatopulmonary syndrome after methadone withdrawal: a case report with implications for disease mechanism.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2010 Jul;16;870-3 — 2010 Jul — 870-3