The Drug-Induced Respiratory Disease Website

Coronary artery disease (acute) - Myocardial ischemia/infarction

Including acute coronary artery disease or spasm and acute ST segment elevation on ECG/EKG. See also under Xg, XIIo and XIIaf

Armstrong F, McCurdy MT, Heavner MS

Synthetic Cannabinoid-Associated Multiple Organ Failure: Case Series and Literature Review.

Pharmacotherapy 2019 Apr;39;508-513 — 2019 Apr — 508-513

Mir A, Obafemi A, Young A, Kane C

Myocardial infarction associated with use of the synthetic cannabinoid K2.

Pediatrics 2011 Dec;128;e1622-7 — 2011 Dec — e1622-7

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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