The Drug-Induced Respiratory Disease Website
See PMID 29369189. (Fr: PnP a eosinophiles). See also under Ie (Acute eosinophilic pneumonia), Xa (DRESS), XVb and XIXc. DI PIE may manifest with fever, dyspnea and wheezes. Eosinophilia can be present in blood, BAL and/or tissue (XVb). Blood and BAL eosinophilia (XIXc) may suffice to secure the diagnosis without recourse to the lung biopsy. Imaging is similar to PIE of other causes. PIE can be part of the DRESS syndrome (Xa), a systemic illness with a cutaneous rash, hematologic abnormalities and deep-seated organ involvement. A few drugs may cause PIE and eosinophilic granulomatosis and polyangiitis (EGPA) formerly known as the Churg-Strauss syndrome) (Xh). Drugs causing eosinophilia at PMID 15062599, 30256812
Publications
61-Year-Old Man With Shortness of Breath and Cough.
Mayo Clinic proceedings 2021 Jul 02;; — 2021 Jul 02
Ustekinumab Associated with Chronic Eosinophilic Pneumonia.
The Journal of asthma : official journal of the Association for the Care of Asthma 2020 Sep 22;;1-6 — 2020 Sep 22 — 1-6
Association of Noninfectious Pneumonia With Ustekinumab Use.
JAMA dermatology 2018 Dec 12;; — 2018 Dec 12
[Ustekinumab-induced eosinophilic pneumonia during the course of ustekinumab therapy for plaque psoriasis].
Annales de dermatologie et de venereologie 2015 Mar;142;193-6 — 2015 Mar — 193-6
Psoriasis vulgaris complicated by eosinophilic pneumonia during ustekinumab treatment.
European journal of dermatology : EJD 2013 May-Jun;23;396-7 — 2013 May-Jun — 396-7