The Drug-Induced Respiratory Disease Website

Anticoagulants, oral (vitamin K antagonists-VKA)

Vocal cord hematoma

May cause UAO

Kerr HD, Kwaselow A

Vocal cord hematomas complicating anticoagulant therapy.

Annals of emergency medicine 1984 Jul;13;552-3 — 1984 Jul — 552-3

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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