The Drug-Induced Respiratory Disease Website
Typically noncardiac. Includies chest tightness. See also under pill-induced esophageal pathologies under XIh, XIi, XIk and XIax that may cause substernal pain. Dedicated review at PMID 9403280. See also under Vi. Can be substernal, or in other areas of the chest. Can be acute, transfixiating and worrisome. Sometimes called 'acute chest syndrome'. Lung findings on imaging can be minimal. Depending on drug and patient, this may correspond to acute pleuritis or pleuro-pneumonitis, subpleural consolidation, GERD, pulmonary vasospasm, tracheal irritation, acute coronary syndrome or remain unexplained (PMID 30697107). See also under pleuritic chest pain (XIc), drug-induced lupus, pleuro-pulmonary lupus and acute coronary syndrome. Differential diagnosis on imaging at PMID 26373647
Publications
Triptans and chest symptoms: the role of pulmonary vasoconstriction.
Cephalalgia : an international journal of headache 2004 Apr;24;298-304 — 2004 Apr — 298-304
Drug-induced chest pain and myocardial infarction. Reports to a national centre and review of the literature.
European journal of clinical pharmacology 1997;53;105-10 — 1997 — 105-10