Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website

XXIV.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

See PMID 29369189. (Fr: PnP a eosinophiles). See also under Ie (Acute eosinophilic pneumonia), Xa (DRESS), XVb and XIXc. DI PIE may manifest with fever, dyspnea and wheezes. Eosinophilia can be present in blood, BAL and/or tissue (XVb). Blood and BAL eosinophilia (XIXc) may suffice to secure the diagnosis without recourse to the lung biopsy. Imaging is similar to PIE of other causes. PIE can be part of the DRESS syndrome (Xa), a systemic illness with a cutaneous rash, hematologic abnormalities and deep-seated organ involvement. A few drugs may cause PIE and eosinophilic granulomatosis and polyangiitis (EGPA) formerly known as the Churg-Strauss syndrome) (Xh). Drugs causing eosinophilia at PMID 15062599, 30256812

Publications

Kampman A, Keulers L, der Maten JV, der Meij JV, Bethlehem C

A Severe Case of Isotretinoin Induced Eosinophilic Pneumonia and Pericardial Effusion, a Case Report.

Current drug safety 2024 Jan 24;; — 2024 Jan 24

De Giacomi F, Decker PA, Vassallo R, Ryu JH

Acute Eosinophilic Pneumonia: Correlation of Clinical Characteristics With Underlying Cause.

Chest 2017 08;152;379-385 — 2017 08 — 379-385

Oliviero G, Constans P, Caby I, De Rohan Chabot P, Lacherade JC

[Lung disease induced by isotretinoin].

Revue des maladies respiratoires 1995;12;631-3 — 1995 — 631-3