Philippe Camus, M.D.

Dijon, France

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XIV.a

Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)

Lone, isolated, free-flowing pleural effusion on imaging. See other forms of pleural effusions under Vb, d, e, g, h, i, m which may present similarly on imaging. The effusion can be uni- or bilateral. More often a lymphocyte-, mixed or neutrophil-rich exudate. At times the effusion is eosipophil-rich. Pleural effusion can be present with the acute clinical phase of severe drug-induced ILD (e.g. methotrexate lung; PMID 16840219). In general, pleural effusion in the context of drug-induced ILD or pulmonary edema is not tabulated under this heading. ANA-panel indicated to diagnose drug-induced lupus PMID 10424528

Publications

Hawatmeh A, Thawabi M, Jmeian A, Shaaban H, Shamoon F

Amiodarone-induced loculated pleural effusion without pulmonary parenchymal involvement: A case report and literature review.

Journal of natural science, biology, and medicine 2017 Jan-Jun;8;130-133 — 2017 Jan-Jun — 130-133

Ya?ar Bilge NS, Gönüllü E, Ka?ifo?lu T, Korkmaz C

Amiodarone-induced pleural fluid is not always accompanied by a risk factor.

Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 2012 May;12;281-2 — 2012 May — 281-2

Uong V, Nugent K, Alalawi R, Raj R

Amiodarone-induced loculated pleural effusion: case report and review of the literature.

Pharmacotherapy 2010 Feb;30;218 — 2010 Feb — 218

Gonzalez-Rothi RJ, Hannan SE, Hood CI, Franzini DA

Amiodarone pulmonary toxicity presenting as bilateral exudative pleural effusions.

Chest 1987 Jul;92;179-82 — 1987 Jul — 179-82