The Drug-Induced Respiratory Disease Website

Mercury fumes/vapor

Chemical (toxic) pneumonitis

Zambratto J, Gottesman E, Hasan Z, Heuser W, Kuschner CE, Mundanchira G, Spaeth KR, Nogar J

Extracorporeal Membrane Oxygenation in the Treatment of Acute Elemental Mercury Inhalation Toxicity.

Chest 2025 Mar;167;e71-e74 — 2025 Mar — e71-e74

Lilis R, Miller A, Lerman Y

Acute mercury poisoning with severe chronic pulmonary manifestations.

Chest 1985 Aug;88;306-9 — 1985 Aug — 306-9

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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