The Drug-Induced Respiratory Disease Website
See also PMIDs 31612562, 34359324. Several drugs can cause a mimic of naturally-occurring endo- and/or extra-thoracic sarcoid-like reaction/sarcoidosis, or a flare of previously diagnosed sarcoidosis (particularly with the use of interferon, anti-TNF agents, or immune checkpoint inhibitors (PMID: 27504482). Both the timing of exposure to the drug and the effect of discontinuation are important to evaluate whether the condition is drug-related. Examination of the skin including scars and/or tatoo edges for evidence of granuloma can be rewarding (PMIDs 24239377, 33905479, 34359324). See also under VIIa, VIIe, Xl.
Publications
El Jammal T, Jamilloux Y, Gerfaud-Valentin M, Richard-Colmant G, Weber E, Bert A, Androdias G, Sève P
Challenging Mimickers in the Diagnosis of Sarcoidosis: A Case Study.
Diagnostics (Basel, Switzerland) 2021 Jul 12;11; — 2021 Jul 12
Lambert N, Hansen I, El Moussaoui M, Giot JB, Vercheval C, Lommers É, Somja J, Moutschen M, Maquet P
Lung and liver sarcoidosis-like reaction induced by tocilizumab.
British journal of clinical pharmacology 2021 Apr 26;; — 2021 Apr 26
Pérez-De-Lis M, Retamozo S, Flores-Chávez A, Kostov B, Perez-Alvarez R, Brito-Zerón P, Ramos-Casals M
Autoimmune diseases induced by biological agents. A review of 12,731 cases (BIOGEAS Registry).
Expert opinion on drug safety 2017 Nov;16;1255-1271 — 2017 Nov — 1255-1271
Sarcoidosis induced by tocilizumab: a paradoxical event?
The Journal of rheumatology 2013 Oct;40;1773-4 — 2013 Oct — 1773-4