The Drug-Induced Respiratory Disease Website

Cocaine

Aortic dissection

Greve D, Funke J, Khairi T, Montagner M, Starck C, Falk V, Sá MPBO, Kurz SD

Cocaine-Related Aortic Dissection: what do we know?

Brazilian journal of cardiovascular surgery 2020 10 01;35;764-769 — 2020 10 01 — 764-769

Niclauss L, Delay D, von Segesser LK

Type A dissection in young patients.

Interactive cardiovascular and thoracic surgery 2011 Feb;12;194-8 — 2011 Feb — 194-8

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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