The Drug-Induced Respiratory Disease Website

Chlorpromazine

Laryngospasm (a.k.a. laryngismus)

Low base of evidence

Nishikawa T, Munakata K

[Drug-induced laryngospasm].

Masui. The Japanese journal of anesthesiology 1997 Feb;46;276-8 — 1997 Feb — 276-8

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

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