The Drug-Induced Respiratory Disease Website

Amiodarone

Pulmonary embolism - Venous thrombosis/thrombo-embolism

A possibility with intravenous amiodarone

Spiering M

Peripheral amiodarone-related phlebitis: an institutional nursing guideline to reduce patient harm.

Journal of infusion nursing : the official publication of the Infusion Nurses Society 2014 Nov-Dec;37;453-60 — 2014 Nov-Dec — 453-60

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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