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The Drug-Induced Respiratory Disease Website

Can cause cardiac tamponade. A.k.a. serositis. Pleural and/or pericardial effusion w/wo pulmonary infiltrates in the context of ANA or antimitochondrial antibodies. Effusions tend to disappear upon drug discontinuance. ANA titers decrease more slowly or may persist indefinitely. See under XI l

Publications

Fenton ME, Kanthan R, Cockcroft DW

Nitrofurantoin-associated bronchiolitis obliterans organizing pneumonia: report of a case.

Canadian respiratory journal 2008 Sep;15;311-2 — 2008 Sep — 311-2

Schattner A, Von der Walde J, Kozak N, Sokolovskaya N, Knobler H

Nitrofurantoin-induced immune-mediated lung and liver disease.

The American journal of the medical sciences 1999 May;317;336-40 — 1999 May — 336-40