The Drug-Induced Respiratory Disease Website

Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

Arrhythmias-Dysrhythmias, including atrial fibrillation (Review at PMID 15582307), ventricular tachycardia/fibrillation See also under torsades de pointe under XIIt

Publications

Alarfaj M, Goswami A

Cardiotoxicity in yew berry poisoning: A case report and literature review.

The American journal of emergency medicine 2021 May 18;; — 2021 May 18

von der Werth J, Murphy JJ

Cardiovascular toxicity associated with yew leaf ingestion.

British heart journal 1994 Jul;72;92-3 — 1994 Jul — 92-3

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

Diagnosing DIRD

Identify causative drugs

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