The Drug-Induced Respiratory Disease Website

Ecstasy (MDMA)

Myocarditis (can be fulminate/fulminant)

Typically acute. Can be fulminate/fulminant and fatal (PMID 30242316). General review at PMID 28540649. Recent addition to the lst of causal drugs include immune checkpoint inhibitors (PMID 28833116, 29801747)

Publications

Mortelmans LJ, Bogaerts PJ, Hellemans S, Volders W, Van Rossom P

Spontaneous pneumomediastinum and myocarditis following Ecstasy use: a case report.

European journal of emergency medicine : official journal of the European Society for Emergency Medicine 2005 Feb;12;36-8 — 2005 Feb — 36-8

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

Diagnosing DIRD

Identify causative drugs

LATEST CHANGELOG

No activity has been recorded yet.

View full changelog