Philippe Camus, M.D.

Dijon, France

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XXIV.b

Pneumonitis (ILD), acute and/or severe (may cause ARDS)

(Fr: PINS aiguë). Acute, generally bilateral and diffuse pneumonitis. More rapid in onset and/or denser, more extensive and severe than pattern Ib. Can be fulminate in the form of diffuse pulmonary interstitial or alveolar opacities and the ARDS picture (see under IIb). BAL is generally lymphocytic and is also indicated to rule out pneumonia due to Pneumocystis, BCG, viruses or other agents particularly in the immunodepressed. Pathology (lung biopsy is not necessary in the majority; before going for the biopsy, please look at PMID 25950989) may disclose dense NSIP, widespread granulomas, or OP depending both on patient and drug. In severe cases pulmonary edema, DAD and/or DAH may develop. Corticosteroid therapy is indicated if patients progress to acute respiratory failure, once an infection has been carefully and resonably ruled out. Transition to pulmonary fibrosis is very uncommon. The boundary between patterns Ia and Ib may be difficult to delineate. See also under IIb

Publications

Fu M, Feng CM, Cao LJ, Hu XW, Xu QX, Xia HL, Ji ZM, Hu NN, Xie W, Fang Y, Xia DQ, Zhang JQ

Acute Respiratory Distress Syndrome Caused by Occupational Exposure to Waterproofing Spray: A Case Report and Literature Review.

Frontiers in public health 2022;10;830429 — 2022 — 830429

Futatsuya C, Minato H, Okayama Y, Katayanagi K, Kurumaya H, Yuasa M, Nishi K

An Autopsy Case of Idiopathic Pleuroparenchymal Fibroelastosis with Left Vocal Cord Paralysis and a Rapid Deterioration without an Acute Exacerbation.

Internal medicine (Tokyo, Japan) 2020 Jun 15;59;1541-1547 — 2020 Jun 15 — 1541-1547

Harada T, Hirabayashi Y, Takayama-Isagawa Y, Sakamoto H, Kawaishi M, Hara H, Aizawa S

Pulmonary Injury from Waterproofing Spray During a Hike.

Wilderness & environmental medicine 2017 Dec;28;327-331 — 2017 Dec — 327-331

Heinzer R, Ribordy V, Kuzoe B, Lazor R, Fitting JW

Recurrence of acute respiratory failure following use of waterproofing sprays.

Thorax 2004 Jun;59;541-2 — 2004 Jun — 541-2

Lazor-Blanchet C, Rusca S, Vernez D, Berry R, Albrecht E, Droz PO, Boillat MA

Acute pulmonary toxicity following occupational exposure to a floor stain protector in the building industry in Switzerland.

International archives of occupational and environmental health 2004 May;77;244-8 — 2004 May — 244-8

Acute respiratory illness linked to use of aerosol leather conditioner--Oregon, December 1992.

MMWR. Morbidity and mortality weekly report 1993 Jan 08;41;965-7 — 1993 Jan 08 — 965-7