The Drug-Induced Respiratory Disease Website

Baclofen

Disordered breathing pattern - Cheynes-Stokes respiration

Generally occurring during sleep. See also under IXb, IXu, IXq

Srivastava S, Hoon A, Ogborn J, Johnston M

Acute onset rhythmic hiccup-like respirations secondary to oral baclofen toxicity.

Pediatric neurology 2014 Aug;51;252-4 — 2014 Aug — 252-4

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

No activity has been recorded yet.