The Drug-Induced Respiratory Disease Website

Baclofen

Hiccup

For review see Bagheri et al. 1999 (PMID: 10216420) and Thompson and Landry 1997 (PMID 9066948)

Srivastava S, Hoon A, Ogborn J, Johnston M

Acute onset rhythmic hiccup-like respirations secondary to oral baclofen toxicity.

Pediatric neurology 2014 Aug;51;252-4 — 2014 Aug — 252-4

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

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