The Drug-Induced Respiratory Disease Website
Pericarditis (i.e. pericardial inflammation) is usually heralded by acute mediothoracic chest pain (PMID 10878205). Large effusions can be ANA positive and cause pericardial tamponade. When present as a longterm sequela, pericardial thickening may cause restriction and constriction. See also under Vc, d, g, m and XIIk (PMID 20511488, 23376916)
Publications
Alectinib-Induced Pleural and Pericardial Effusions in ALK-Positive NSCLC.
Case reports in oncology 2021 Sep-Dec;14;1323-1327 — 2021 Sep-Dec — 1323-1327
Gadgeel SM, Gandhi L, Riely GJ, Chiappori AA, West HL, Azada MC, Morcos PN, Lee RM, Garcia L, Yu L, Boisserie F, Di Laurenzio L, Golding S, Sato J, Yokoyama S, Tanaka T, Ou SH
Safety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK-rearranged non-small-cell lung cancer (AF-002JG): results from the dose-finding portion of a phase 1/2 study.
The Lancet. Oncology 2014 Sep;15;1119-28 — 2014 Sep — 1119-28