The Drug-Induced Respiratory Disease Website

Chloroquine

Respiratory arrest - Apnea

See also under IXd, IXa, IXd, IXs, XIIm. Review of causal agents on PMID 30553870

MARKOWITZ HA, MCGINLEY JM

CHLOROQUINE POISONING IN A CHILD.

JAMA 1964 Sep 21;189;950-1 — 1964 Sep 21 — 950-1

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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