The Drug-Induced Respiratory Disease Website

Tofacitinib

Cryptococcus pulmonary and/or systemic infection

C neoformans. C laurentis (PMID 29519311)

Seminario-Vidal L, Cantrell W, Elewski BE

Pulmonary Cryptococcosis in the Setting of Tofacitinib Therapy for Psoriasis.

Journal of drugs in dermatology : JDD 2015 Aug;14;901-2 — 2015 Aug — 901-2

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

No activity has been recorded yet.