The Drug-Induced Respiratory Disease Website

Cardiopulmonary resuscitation (CPR)

Pneumopericardium

Can be associated with or result from pneumomediastinum

Flentje M, Krüger M, Ruschulte H

[Pneumopericardium due to thorax compression : Overlooked resuscitation injury].

Der Anaesthesist 2015 12;64;943-947 — 2015 12 — 943-947

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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