The Drug-Induced Respiratory Disease Website
The broad term 'cardiotoxicity' encompasses several entities and patterns of cardiac injury including subclinical change in LVEF or cardiac biomarkers, cardiomyopathy, heart failure, AV heart block, conduction abnormalities, myocarditis, myocardial fibrosis, dysrrhythmias, pericarditis, pericardial effusion, tamponade, syncope, cardiac/cardiopulmonary arrest and/or valvular heart dysfunction or disease. Pulmonary edema and pleural effusion may be the annunciating signs and symptoms of cardiotoxicity (PMID 1403060). Cardiotoxicity is a significant hurdle of novel anticancer agent use including the immune checkpoint inhibitors (PMID 25210198, 25574894, 27732808, 29912044, 29980467, 30433897). Can be life-threatening or fatal (PMID 29980467)
Publications
Human Poisoning due to Delphinium Species in the Himalayan Region of Nepal: A Case Report.
JNMA; journal of the Nepal Medical Association 2020 Dec 31;58;1086-1088 — 2020 Dec 31 — 1086-1088
Fatal heart block from intentional yew tree () ingestion: a case report.
European heart journal. Case reports 2020 Feb;4;1-4 — 2020 Feb — 1-4
Herbal Cardiotoxicity: Can Mother Nature Hurt the Heart?
The Canadian journal of cardiology 2016 Mar;32;291-3 — 2016 Mar — 291-3
Hypovolemic shock and mortality after ingestion of Tripterygium wilfordii hook F.: a case report.
International journal of cardiology 1995 Apr;49;173-7 — 1995 Apr — 173-7