The Drug-Induced Respiratory Disease Website
Can be uni- or bilateral. Pneumomediastinum can be present as an associated finding. Pneumothorax can develop as a complication of drug-induced pleural fibrosis or fibroelastosis (see under IV c) and it can difficult to treat as the lung may reexpand poorly. Pneumothorax can also occur as a complication of drug-induced cavitation or thinning of pulmonary tumors including metastases (See XIu). The association with therapy with drugs is confounded by indication (PMID 23801882) as pneumothorax can also occur idiopathically. Novel targeted agents may cause tumor necrosis, cavitation of metastatic lung nodules and difficult-to-treat pneumothorax
Publications
Transbronchial lung cryobiopsy: prospective safety evaluation and 90-day mortality after a standardized examination protocol.
Therapeutic advances in respiratory disease 2022 Jan-Dec;16;17534666221077562 — 2022 Jan-Dec — 17534666221077562
Wälscher J, Groß B, Eberhardt R, Heussel CP, Eichinger M, Warth A, Lasitschka F, Herth FJF, Kreuter M
Transbronchial Cryobiopsies for Diagnosing Interstitial Lung Disease: Real-Life Experience from a Tertiary Referral Center for Interstitial Lung Disease.
Respiration; international review of thoracic diseases 2019;97;348-354 — 2019 — 348-354
High Complication Rate after Introduction of Transbronchial Cryobiopsy into Clinical Practice at an Academic Medical Center.
Annals of the American Thoracic Society 2017 Jun;14;851-857 — 2017 Jun — 851-857
Diagnostic Yield and Complications of Transbronchial Lung Cryobiopsy for Interstitial Lung Disease. A Systematic Review and Metaanalysis.
Annals of the American Thoracic Society 2016 10;13;1828-1838 — 2016 10 — 1828-1838