The Drug-Induced Respiratory Disease Website

Chlorine gas (dichlorine: Cl2)

Reactive airway dysfunction syndrome (RADS)

(Fr: Sd de dysfonction des voies aériennes)

Clark KA, Karmaus WJ, Mohr LC, Cai B, Balte P, Gibson JJ, Ownby D, Lawson AB, Vena JE, Svendsen ER

Lung Function before and after a Large Chlorine Gas Release in Graniteville, South Carolina.

Annals of the American Thoracic Society 2016 Mar;13;356-63 — 2016 Mar — 356-63

Chlorine gas release associated with employee language barrier--Arkansas, 2011.

MMWR. Morbidity and mortality weekly report 2012 Dec 07;61;981-5 — 2012 Dec 07 — 981-5

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

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