Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website

XXIV.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

See PMID 29369189. (Fr: PnP a eosinophiles). See also under Ie (Acute eosinophilic pneumonia), Xa (DRESS), XVb and XIXc. DI PIE may manifest with fever, dyspnea and wheezes. Eosinophilia can be present in blood, BAL and/or tissue (XVb). Blood and BAL eosinophilia (XIXc) may suffice to secure the diagnosis without recourse to the lung biopsy. Imaging is similar to PIE of other causes. PIE can be part of the DRESS syndrome (Xa), a systemic illness with a cutaneous rash, hematologic abnormalities and deep-seated organ involvement. A few drugs may cause PIE and eosinophilic granulomatosis and polyangiitis (EGPA) formerly known as the Churg-Strauss syndrome) (Xh). Drugs causing eosinophilia at PMID 15062599, 30256812

Publications

Brancaleone P, Descamps O, Piquet M, Detry G, Mignon M, Weynand B

[Sertraline-induced chronic eosinophilic pneumonia].

Revue des maladies respiratoires 2021 Feb 10;; — 2021 Feb 10

Muftah M, Nassri R, Nassri A, Harford P

Sertraline-Induced Acute Eosinophilic Pneumonia.

Current drug safety 2018;13;196-199 — 2018 — 196-199

Thornton C, Maher TM, Hansell D, Nicholson AG, Wells AU

Pulmonary fibrosis associated with psychotropic drug therapy: a case report.

Journal of medical case reports 2009 Nov 16;3;126 — 2009 Nov 16 — 126

Haro M, Rubio M, Xifré B, Castro P

[Acute eosinophilic pneumonia associated to sertraline].

Medicina clinica 2002 Nov 09;119;637-8 — 2002 Nov 09 — 637-8

Barnés MT, Bascuñana J, García B, Alvarez-Sala JL

Acute eosinophilic pneumonia associated with antidepressant agents.

Pharmacy world & science : PWS 1999 Oct;21;241-2 — 1999 Oct — 241-2