The Drug-Induced Respiratory Disease Website

Sevoflurane

Carboxyhemoglobinemia (CO poisoning)

Via carbon monoxide (CO) poisoning

Fatheree RS, Leighton BL

Acute respiratory distress syndrome after an exothermic Baralyme-sevoflurane reaction.

Anesthesiology 2004 Aug;101;531-3 — 2004 Aug — 531-3

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

No activity has been recorded yet.