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The Drug-Induced Respiratory Disease Website

Corresponds to circulating autoantibodies (ANA, anti-dsDNA, multispecific ANCA). Titers can be very high and/or multispecific and tend to diminish in a few weeks or months upon drug discontinuance. Autoimmunity can be asymptomatic or is with various clinical presentations including pulmonary vascultis or hemorrhage (PMID 20015613). See also under patterns IIIa, IIIb, IIId, Vd, VId, and  Xb, d, h, j, m, s, x, y, ac, ah, am, ao, aw, ax, ay

Publications

Woodring T, Abraham R, Frisch S

A case of probable trimethoprim-sulfamethoxazole induced circulating antineutrophil cytoplasmic antibody-positive small vessel vasculitis.

Dermatology online journal 2017 Aug 15;23; — 2017 Aug 15