The Drug-Induced Respiratory Disease Website
See PMID 29369189. (Fr: PnP a eosinophiles). See also under Ie (Acute eosinophilic pneumonia), Xa (DRESS), XVb and XIXc. DI PIE may manifest with fever, dyspnea and wheezes. Eosinophilia can be present in blood, BAL and/or tissue (XVb). Blood and BAL eosinophilia (XIXc) may suffice to secure the diagnosis without recourse to the lung biopsy. Imaging is similar to PIE of other causes. PIE can be part of the DRESS syndrome (Xa), a systemic illness with a cutaneous rash, hematologic abnormalities and deep-seated organ involvement. A few drugs may cause PIE and eosinophilic granulomatosis and polyangiitis (EGPA) formerly known as the Churg-Strauss syndrome) (Xh). Drugs causing eosinophilia at PMID 15062599, 30256812
Publications
Sulfonamide-induced acute eosinophilic pneumonia requiring extracorporeal membrane oxygenation support: a case report.
Critical care science 2023;35;239-242 — 2023 — 239-242
Interstitial Myocarditis Following the Clinical and Experimental Use of Sulfonamide Drugs.
The American journal of pathology 1942 Jan;18;109-21 — 1942 Jan — 109-21
Sulphasalazine and lung toxicity.
The European respiratory journal 2002 Apr;19;756-64 — 2002 Apr — 756-64
[Labile infiltrate induced by a long-acting sulfonamide].
Marseille medical 1969;106;891-3 — 1969 — 891-3
Migratory pneumonia with eosinophilia associated with sulfonamide administration.
Archives of internal medicine 1967 Jul;120;85-9 — 1967 Jul — 85-9
Pulmonary infiltration and eosinophilia associated with sulfasalazine therapy for ulcerative colitis: a case report and review of literature.
Internal medicine (Tokyo, Japan) 1992 Jan;31;108-13 — 1992 Jan — 108-13