The Drug-Induced Respiratory Disease Website

Anabolic androgenic steroids

Pulmonary edema, cardiogenic

(Fr: OAP cardiogénique). Can result from left or biventricular dysfunction/failure. See also under XIIa, XIId, XIIai

Ilonze OJ, Enyi CO, Ilonze CC

Cardiomyopathy and heart failure secondary to anabolic-androgen steroid abuse.

Proceedings (Baylor University. Medical Center) 2022;35;363-365 — 2022 — 363-365

Hernández-Guerra AI, Tapia J, Menéndez-Quintanal LM, Lucena JS

Sudden cardiac death in anabolic androgenic steroids abuse: case report and literature review.

Forensic sciences research 2019;4;267-273 — 2019 — 267-273

Garner O, Iardino A, Ramirez A, Yakoby M

Cardiomyopathy induced by anabolic-androgenic steroid abuse.

BMJ case reports 2018 Jul 23;2018; — 2018 Jul 23

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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