The Drug-Induced Respiratory Disease Website
(Fr: PnP avec granulomes). 2018 review at PMID 29698718. Characteristically nonnecrotizing, noninfectious, sterile granulomas. Although this is a pathologic pattern, the condition is suspected on a miliary appearance on imaging. Hilar/mediastinal lymphadenopathy can be present. May mimic pulmonary and/or systemic sarcoidosis. Concomittant skin lesions may show granulomas. A confirmarptory lung biopsy may be required (See under Pathology XIV). Careful exclusion of mycobacterial, fungal and Pneumocystis infection is crucial (See PMID 10678649, 18054121, 17257125).
Publications
Shisha smoking as a possible cause of bilateral granulomatous lung lesions.
Respirology case reports 2018 Dec;6;e00374 — 2018 Dec — e00374
A 20-year-old man with fever, chest pain, and lung nodules.
Chest 2011 Nov;140;1378-1381 — 2011 Nov — 1378-1381