The Drug-Induced Respiratory Disease Website

Vicks Vaporub TM (R)

Paraffinoma - Lipidoma (ELP in the form of a nodule or mass)

Cherrez Ojeda I, Calderon JC, Guevara J, Cabrera D, Calero E, Cherrez A

Exogenous lipid pneumonia related to long-term use of Vicks VapoRub® by an adult patient: a case report.

BMC ear, nose, and throat disorders 2016;16;11 — 2016 — 11

Subramanian S, Kherdekar SS, Babu PG, Christianson CS

Lipoid pneumonia with Cryptococcus neoformans colonisation.

Thorax 1982 Apr;37;319-20 — 1982 Apr — 319-20

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

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