The Drug-Induced Respiratory Disease Website

Ticagrelor

Disordered breathing during sleep - Sleep apnea

Including prolongation of apnea. PMID 27735059, 33965721.

Revol B, Jullian-Desayes I, Tamisier R, Puel V, Mallaret M, Joyeux-Faure M, Pépin JL

Ticagrelor and Central Sleep Apnea.

Journal of the American College of Cardiology 2018 May 22;71;2378-2379 — 2018 May 22 — 2378-2379

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

LATEST CHANGELOG

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